Grapes
Eating fresh grapes may prevent the accumulation of harmful oxidized
cholesterol as well as the development of atherosclerotic lesions.
According to the study, as reported in the Journal of Nutrition (vol.
135, pp. 722-728, 2005.), naturally occurring antioxidants in fresh
grapes known as polyphenols are believed to be responsible for this
beneficial impact.
In order to ensure the scientific validity of grape health studies, a
representative sample of fresh California grapes was collected,
freeze-dried and ground into an edible grape powder. The grape powder
used in this study contains all of the biologically active compounds
found in fresh grapes.
"We found a remarkable reduction in the development of atherosclerosis
following consumption of grape powder," said principal investigator
Bianca Fuhrman, Senior Scientist at the Lipid Research Laboratory
headed by Dr. Michael Aviram at the Rambam Medical Center in Israel .
"Grapes contain an abundance of powerful antioxidants that appear to
inhibit an array of critical factors that can cause atherosclerosis."
Atherosclerosis, also known as hardening of the arteries, is the result
of cholesterol build-up on the arterial wall, which leads to blockage
of the vessels that supply blood to the heart or the brain, resulting
in a heart attack or stroke, respectively. Blood cholesterol is carried
throughout the body by two lipoproteins. Low density lipoprotein (LDL),
also known as the "bad" cholesterol, deposits cholesterol in arterial
walls when it is present in excess. High density lipoprotein (HDL), or
the "good" cholesterol, removes the excess cholesterol from the
arteries to the liver and out of the body. When cholesterol is damaged
by oxidation, such as oxidized LDL cholesterol, it is more easily
deposited in the arterial walls, leading to a blockage of the vessels.
Diseases caused by atherosclerosis are the leading cause of illness and
death in the U.S.
Dr. Fuhrman's study showed that grape polyphenols reduced oxidative
stress, increased serum antioxidant capacity, reduced cell uptake of
oxidized LDL cholesterol and decreased the oxidation of LDL in general.
These processes eventually reduce the accumulation of cholesterol in
the cells and prevent foam cell formation, thus inhibiting the
development of atherosclerosis.
"We are pleased to see studies such as this further the mounting
evidence that grapes exert a protective role in heart health," said
Kathleen Nave, president of the California Table Grape Commission.
"Importantly, this work provides insight that grapes impact a number of
mechanisms that may lead to a reduction in atherosclerosis."
Make 5 to 10 servings of fruits and vegetables per day your goal and
lead your children towards a life of health, happiness, vitality, and
longevity.
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