Menu



error This forum is not active, and new posts may not be made in it.
PromoteFacebookTwitter!
Luis Miguel Goitizolo

1162
61587 Posts
61587
Invite Me as a Friend
Top 25 Poster
Person Of The Week
RE: ARE WE NOW IN THE END TIMES?
4/10/2016 4:28:06 PM

HOW THE PANAMA PAPERS INVESTIGATION UNFOLDED

BY ON 4/9/16 AT 3:40 PM
World's Wealthy Deny Links In Panama Papers Leak

Investigative reporter Gerard Ryle has made a career out of exposing corruption on a global scale. He’s won multiple awards, written an acclaimed book and exposed the financial wrongdoings of some of the world’s most powerful people. But, while highly respected in journalistic circles, he was far from being a household name. Now, in the wake of the Panama Papers exposé , he has propelled himself and the small, charitable organisation he runs, the International Consortium of Investigative Journalists, firmly into the media spotlight.

Before becoming the first non-American director of the ICIJ , which is based in Washington, Ryle spent 26 years working as an investigative reporter and editor in Australia and Ireland. He uncovered some of the biggest stories in Australian journalism, including the investigation into fraudster Tim Johnston, who duped the Australian, British and Russian governments over a fuel pill which he claimed would revolutionize the way energy was used worldwide . But even that pales in comparison with his latest project—the Panama Papers leak.

Ryle coordinated with more than 100 media organizations to analyze the 11.5 million files that exposed a global system of tax evasion. The documents implicate everyone from world leaders such as the Russian President Vladimir Putin , the Syrian President Bashir-Al Assad , relatives of China’s President President Xi Jinping and the Icelandic Prime Minister Sigmundur David Gunlagsson, who resigned earlier this week. The offshore investments of the father of the British Prime Minister, David Cameron, also were revealed—although there is no suggestion that Cameron or his father broke the law. Celebrities such as Simon Cowell , Jackie Chan and Sarah Ferguson, Duchess of York, also were named in this unprecedented leak which covers a period spanning from the 1970s to the spring of 2016.

Now, the story is out, the offshore trading industry is under scrutiny, and the rich and powerful around the globe are squirming, but the question remains—how did this small organization pull this off? I caught up with Ryle to get some answers.

I guess you’ve had a busy few days since the story broke on Sunday?

It’s been non-stop here, the phones just keep ringing. I suppose I’ll miss it when it ends.

How did you first come across this story?

The documents were first obtained by a journalist called Bastian Obermayer, 38, a reporter for the German newspaper Süddeutsche Zeitung. We had worked together in the past on other projects, such as last year’s Swiss Leaksinvestigation [which exposed the inner working of HSBC’s Swiss private banking arm]. In 2014 I learned, through Bastian, that the German government had purchased data about Mossack Fonseca [the Panamanian law firm exposed in the recent leak] from a whistleblower. That data was then offered to other tax offices around the world including those in the U.K. and Iceland.

Through Bastian’s contacts we got hold of that data. It was interesting but not super interesting. That leak is unrelated to the data we eventually got but it is part of the history of how this happened. The German government raided the Commerzbank in Frankfurt in February 2015, as a result of the data they had purchased, and Süddeutsche Zeitung ran a story on it. I had a disagreement with Bastian and his colleague Frederick Obermaier, 32, because I didn’t want them to reveal that we had extra information about Mossack Fonseca [in the data]. They said they had to do so. They were right, and I was wrong. They published and then someone contacted them offering more data on Mossack Fonseca. It went from there.

People demonstrate against Iceland's Prime Minister Sigmundur David Gunnlaugsson in Reykjavik, Iceland on Tuesday. Gunnlaugsson became the first major casualty of the Panama Papers revelations, resigning after leaked files showed his wife owned an offshore firm with claims on the country's collapsed banks.
STIGTRYGGUR JOHANNSSON/REUTERS

When did you first see the documents?

Initially, we had about one million documents, which we thought was a lot of material. Bastion received them first, through his contact. When he told me what he had I booked a flight straight to see him in Munich. The three of us then spent about four days looking through the documents.

Demonstrators hold placards during a protest against British Prime Minister David Cameron in Whitehall, central London, Britain on Saturday.
NEIL HALL/REUTERS

Did you immediately realize how important a story this had the potential to be?

Yes, we all agreed this was big. Among the first names we saw were those with links to Robert Mugabe and Muammar el- Qaddafi. We saw enough names from enough different nations to know that we would be able to get an international collaboration [of journalists] together. We arranged a meeting with the editors in chief of Süddeutsche Zeitung— we had to negotiate to stop them publishing the story straight away. They agreed the ICIJ would be in charge of putting together the collaboration. Then I flew to London and met with James Oliver, a producer on the BBC’s Panorama, and David Lea, the former investigations editor of theGuardian. I wanted to know if both the BBC and the Guardian would be in? They said yes, absolutely.

How did you persuade the editors at Süddeutsche Zeitung to go against their journalistic instinct and not publish the moment they saw the documents?

It took a long time. They were being polite but I think their first intention was to publish the story quickly. But, they could see that that we knew what we were doing. Frederick and Bastion were onboard my plan—they knew it was going to take months to go through the documents.

How did you start going through such a vast amount of data?

The documents arrived in parcels. We would have indexed several million and then another million would arrive, and so on. We counted 11.5 million files that we had to index. It included every email sent by the firm over the past 40 years, every passport of every client, it was a motherload really.

When did you decide you were ready to let other journalists in on the secret?

We hosted a meeting in Washington in June 2015 for around 40 to 50 journalists from around the world, who all travelled to the U.S. at their own expense. We rented a room at the National Press Club, where we unveiled the project and the tools we had built for it, which included a virtual newsroom and an effective search system. You can’t just parcel up the documents for the U.K. and give them to the British reporters, you need to give all the reporters access to all the documents at all times. That was the only way the collaboration could work.

How did you decide who to invite to that first meeting?

It was done on trust. We invited people who had worked with us before and who we knew wouldn't waste our time. It wasn't as hard as you might think! We tend to work with reporters, rather than the bosses. Once you get the reporter excited about the story, then they will advocate for it with their bosses.

Did you manage to get all the collaborators together at any point?

We had another bigger meeting in Munich in September, with over 100 reporters. Some editors were there too including the Guardian’s Kathryn Viner who flew over with her deputy Paul Johnson. That meeting lasted two days and was hosted by Süddeutsche— who allowed us to takeover some rooms at their offices in Munich. We didn’t pay for anything as we are a not-for-profit organization, run on a shoestring.

How did you get everyone to agree to keep this huge secret?

We made everyone sign an agreement stating that they weren't allowed to tell anyone what they were working on. The only thing we insisted on is that the ICIJ decided when publication day would be.

Why did you chose to publish now?

We were looking at a lot of different dates. The TV crews had their needs, every country had its own considerations. The Germans wanted to publish on Saturday as that is their big day for news, in the U.S. it’s Sunday and in the U.K. it’s normally Monday. We had planned to go in March then quite late on the Germans realized that Chancellor Merkel was under a lot of pressure, and that the regional elections they had thought would be minor might turn out to be very significant, so then we had to convince everyone to wait for another couple of weeks.

What was your first big discovery among the Panama Papers data?

The first one was Iceland. We knew about it pretty early on but didn't know if was significant—if the prime minister had declared his interest in the offshore company, Wintris [that owned bonds in Iceland’s banks. So, when Iceland's financial sector collapsed in 2008, Wintris became a creditor to those banks—an enormous conflict of interest]. The material on Iceland jumped out at us, we knew it involved the collapse of the banks, and that some of those named were in jail. We needed an Icelandic journalist we could trust and our Swedish partners recommended Johannes Kr. Kristjansson—a freelance reporter, who was quite famous in Iceland.

How hard was it for him to keep secret the fact he was working on a story which could bring down the prime minister?

It was a huge risk for Johannes. He put everything into it. He gave up all his other work for nine months to do the story and lived off his wife. I went over to Iceland to visit him because I realized he must be the loneliest person in the world. We spent a lot of time discussing strategy and how best to manage the confrontation. My policy is always to do whatever it is you would normally do—forget fetishizing another country’s ethical rules. In the end we involved the Swedish television channel, SVT, in the confrontation interview with the Icelandic prime minister which went viral all round world. It was a great moment.

When did the documents concerning David Cameron’s father’s offshore investment fund come to light?

We knew about that early on too. I was keen to get Cameron into the story to head off criticism from the Kremlin that we were focusing on Russia. What had happened was that we put the questions into the Kremlin and the associates of Putin a week in advance of publication and instead of answering them they held a press conference denouncing us and saying it was all a plot. I think Putin thought it was all about him, so we thought we’re going to wait and show it’s not just about him, it’s about everyone.

What was your favorite moment in this epic investigation?

Towards the end, Johannes started saying “Wintris is coming” borrowing fromGame of Thrones and referencing the name of the company linked to the Icelandic prime minister. Then after we published he was saying “Wintris has arrived.” Also, coming into the office the day after publication, stressed and tired after non stop interviews to find that one of my staff had emailed me a photo of the protest outside the parliament in Iceland. The image filled my entire screen—for me that was a real “holy ****” moment.

(Newsweek)

"Choose a job you love and you will not have to work a day in your life" (Confucius)

+2
Luis Miguel Goitizolo

1162
61587 Posts
61587
Invite Me as a Friend
Top 25 Poster
Person Of The Week
RE: ARE WE NOW IN THE END TIMES?
4/10/2016 4:46:42 PM

Unusual freak hailstorm hits Saudi Arabia


An unusual freak hailstorm hit Saudi Arabia on April 6, 2016 covering the desert, streets and entire cities with white icy stones.

The thunderstorms were so powerful that they created a tornado just 100km way from Riyadh.


And here it comes:

freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
Yasser Khalil

Stormy conditions are growing and sweeping across Saudi Arabia since Monday, April 3, 2016.

freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
Yasser Khalil
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
Riyadh

The storm line has now reached central Saudi Arabia where the desert suddenly turned white on April 6, 2016.

freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK

The low is sweeping from North to South and si currently flooding the city of Ta’if in biblical proportions.

freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK

Extreme wind gusts are also accompanying the stormy weather.

freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK

So there is cold air coming from the north and warm air coming from the south. As the clash in the center of the country, they create a kind of belt, responsible for this extreme weather phenomenon.

freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK

Look at this video. Impressive!



Sometimes the strong winds are creating sand tornado and sandstorms. This one was captured just 100km away from Riyadh!

freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
freak hailstorm saudi arabia shelf cloud, freak hailstorm saudi arabia april 2016, freak hailstorm saudi arabia pictures, saudi arabia hail april 6 2016, saudi arabia hail april 6 2016 pictures, photos of saudi arabia hail april 6 2016
via VK
This extreme weather also reached Kuwait, Qatar, Bahrain and western Yemen.

Anomalous is the best terminology I can find!

(
strangesounds.org/)

"Choose a job you love and you will not have to work a day in your life" (Confucius)

+2
Luis Miguel Goitizolo

1162
61587 Posts
61587
Invite Me as a Friend
Top 25 Poster
Person Of The Week
RE: ARE WE NOW IN THE END TIMES?
4/10/2016 5:10:20 PM

HOW MUCH FOR YOUR CHILD? AFGHAN CONDOLENCE PAYMENTS DRAW SCRUTINY

BY ON 4/9/16 AT 8:29 PM
Zabiullah Niazi, 25, was trying to get some sleep after four days of working as an ER nurse in Doctors Without Borders' Kunduz Trauma Center, when in the early hours of October 3 he woke to the sound of bombing striking the hospital. After having his face and hand burnt in an initial blast, a second blast left his arm dangling by a thread. He says he received 200,000 Afghani (about $3,000) from the U.S. military for the accidental bombing.
ANDREW QUILTY

Inside the Doctors Without Borders hospital in Kunduz, northern Afghanistan, Abdul Ghadir, 43, surveys the overturned bed frames, blackened by flames, and the caved-in ceiling and walls dark with soot. His feet crunch across a floor covered in glass shards and ash. “This,” he says, “is the grave of my daughter.”

Amina, Ghadir’s 12-year-old girl, was killed in the early hours of October 3 last year, six days after the Taliban had captured Kunduz. In support of Afghan security forces trying to take back the city, a U.S. military AC-130 gunship repeatedly fired on the hospital. In total, 42 patients, staff and caregivers were killed, and dozens more wounded, in the hourlong attack. The U.S. has since admitted that firing on the hospital was an error.

Earlier this year, in a crowded room at the Kunduz military base, U.S. military officials apologized to some of the victims and handed out condolence payments. For Amina’s death, Ghadir received around $6,000. Those who were wounded received around $3,000.

As the cash was handed out, Ghadir says, he felt desperate and powerless. “The money is obviously not enough compared to the life of my daughter,” he says. But he had borrowed money for Amina’s funeral, and with a large family to provide for, “I had no other choice but to accept what they gave me.”

Two days before the airstrike, a stray bullet hit Amina in the head, and she was rushed to the Doctors Without Borders hospital. After surgery, doctors said they expected a full recovery — Amina would be able to pursue her dreams of becoming a doctor, memorize the Koran and continue studying English at school.

Then the U.S. gunship pummeled the intensive care unit where Amina lay recovering. Like other patients in the ICU, she burned in her bed.

“I took one handful of ash to my wife and said, ‘This is your daughter,’” says Ghadir. He couldn’t find anything else left of Amina to take.

Condolence payments

Condolence payments are a long-standing U.S. military practice, used in Afghanistan since 2005 to acknowledge civilian harm without admitting moral or legal responsibility. U.N. records show that from 2009 through 2015, at least 21,323 Afghan civilians have been killed and 37,413 wounded. While the U.S. military is responsible for a small fraction of that total, it has never fully disclosed the extent of the harm caused or payments made.

Nevertheless, the limited U.S. military records released under the Freedom of Information Act show a startling catalog of collateral damage, demonstrating the often inconsistent, ad hoc nature of condolence payments. In 2012, a man in Helmand province was paid $972.76 after his wife was killed in an operation by the U.S.-led coalition; in Kunar province, a man received $7,337.61 for his son’s death. Because condolence payments are both discretionary and rely on access to the relatives of victims, who often live in insecure areas, some families have likely received nothing at all.

The U.S. military has more than one pot to draw from for the program. The most common source of funds is the Commander’s Emergency Response Program. A 2009 CERP manual states that condolence payments are not compensation for loss but “can be paid to express sympathy and to provide urgent humanitarian relief.”

For most Kunduz victims, that expression of sympathy has not been enough. Several I spoke to were angry they had not been consulted before receiving just a few thousand dollars. Some referred to much larger payments made in Afghanistan, such as the $50,000 compensation paid for each death caused by Sergeant Robert Bales, who murdered 16 civilians in 2012. They were also frustrated by the lack of transparency.

“Making amends to the victims is about much more than the money,” says Marla Keenan, managing director for the Center for Civilians in Conflict, a nonprofit advocacy group. “It can seem incredibly arbitrary if you are the victim and someone shows up on your doorstep with a bag of money.”

In an effort to address such frustrations, General John Nicholson, the new commander of U.S. forces in Afghanistan, traveled to Kunduz in late March and publicly apologized, asking for forgiveness. Nicholson was accompanied by his wife, Norine MacDonald, who met with hospital staff and victims’ families, but the families were disappointed not to meet the general in person.

Keenan praised the personal outreach by Nicholson and MacDonald, but it did little to comfort the victims. Nicholson’s apology might have been more welcome had the victims not already felt so insulted. General John Campbell, the American commander at the time of the airstrike, never explicitly apologized or reached out to Doctors Without Borders. “At that time, we really needed to hear from [the U.S. military],” says Enayatullah Hamdard, a representative of the families of the 14 hospital staff killed. “Instead, they come after five, six months, and they didn’t meet with the families.”

Some Kunduz victims also expressed frustration over how little they knew about the attack. The U.S. has ignored Doctors Without Borders’s repeated calls for an independent investigation and has yet to release the results of an official investigation. “I don’t know what is going on with the U.S. Army in Afghanistan. On one hand, they are helping the Afghan government; on the other side, they are killing Afghan citizens,” says Turailai Salih, a hospital storekeeper who suffered a shrapnel wound. “Why did they do this?”

The victims also say the condolence payments are not adequate to cover what they have lost. “We know that no amount of money can compensate for the tragic loss of life,” says Brigadier General Charles Cleveland, the U.S. military deputy communications chief in Afghanistan. The payments, he says, “are an expression of condolences only; they are not compensation.”

'You are nothing'

Some Kunduz victims asked for compensation in addition to the condolence payments. In response, U.S. military officers distributed compensation claim forms that Cleveland says will be adjudicated under the Foreign Claims Act (FCA), which allows awards of up to $100,000. That was welcome news to the victims, many of whom lost breadwinners or need long-term medical care.

Zabiullah Niazi, a hospital nurse, was his family’s sole provider, earning around $400 a month. His left arm was severed just below the shoulder, his right hand damaged and his left eye permanently blinded by the attack. He received $3,000. Reports often compare the relatively small condolence amounts to Afghanistan’s low average wages. This fails to recognize that for skilled professionals like Niazi who support large families, it is a pittance.

Niazi says he accepted the condolence payment only because he believed additional compensation would be paid. His medical expenses alone have so far amounted to $6,000. He is now furious after legal experts from Doctors Without Borders and elsewhere concluded that Kunduz victims are almost certainly ineligible to receive FCA compensation. That is because the FCA pays only when the harm was caused by a noncombat action; for example, a traffic accident, not an airstrike that targeted a hospital in error.

“We realized this form [distributed by the U.S. military] was a legal dead end,” says Guilhem Molinie, Afghanistan country director with Doctors Without Borders. “What is this? This is manipulation of people, giving them hope.”

Cleveland did not directly address Newsweek ’s question about whether the FCA would allow for compensation in this case, saying a determination would be made once a claim was received.

Hina Shamsi, director of the American Civil Liberties Union’s National Security Project, says any lawsuit for compensation by the Kunduz victims is unlikely to succeed. “I wouldn’t want to rule it out, but the hurdles are very significant,” she says. For cases brought by foreign citizens concerning rights violations by the U.S. military abroad, “U.S. courts have a shameful record of dismissing them on jurisdiction or immunity grounds without getting to the merits.”

Keenan says the U.S. should adopt a comprehensive standing policy to make amends to all civilian victims wherever incidents occur. “It is absolutely key to address civilian harm in the right way,” she says.

Without proper compensation, the Kunduz victims will not be able to move on with their lives, says Molinie. At the hospital, a large fence has been erected to obscure the view of the bombed building at the request of the staff, who could no longer bear to see it. “They know who was killed where in the hospital,” he says.

One of those staff members is Salih, the storekeeper. His easy smile disappears as he recalls rushing through the hospital that night, hearing the screams of patients and seeing colleagues die in front of him. Salih brightens, however, as he tells a new joke among his friends in Kunduz: “You are nothing. You just cost $3,000,” he says, smiling wryly. “Every Afghan is $3,000 for America. They give you money, and then you can go.”

(Newsweek)


"Choose a job you love and you will not have to work a day in your life" (Confucius)

+2
Luis Miguel Goitizolo

1162
61587 Posts
61587
Invite Me as a Friend
Top 25 Poster
Person Of The Week
RE: ARE WE NOW IN THE END TIMES?
4/10/2016 11:40:06 PM

Well Regulated: Inside an Indiana Militia

, michael.adams@indystar.com12:41 p.m. EDT April 9, 2016

IndyStar reporter Michael Anthony Adams gained access to one of Indiana’s largest militias to give you an inside look at how its members train and prepare for worst case scenarios. Michael Anthony Adams/IndyStar

The militia movement is growing. See what drives members to join and train with one of Indiana's largest militias.



Jason Goodwin, a corporal in the Indiana Volunteer Militia, stands with his rifle in Echo Lake Park on Sunday, March 20, 2016, during the militia's bi-monthly training camp.
(Photo: Michael Anthony Adams / IndyStar)

David Nantz carefully pushed aside a grouping of bare branches at the tree line of Echo Lake Park, then stood still. He listened for movement, playing the role of the enemy attempting to infiltrate a base that had been forged by his men.

It was Sunday, training day, and the Indiana Volunteer Militia, one of the largest militias in the state, was practicing how to set up a patrol base and establish perimeter security. Their mission was to fashion a few shelters and secure the base before Nantz made entry.

In a real world scenario, Nantz said, when the grid goes down, you have to know how to protect yourself and your family.

Recent high-profile standoffs with federal law enforcement agencies in
Nevada and Oregon, as well as a controversial appearance by a militia group during the police brutality protests last year in Ferguson following the shooting of Michael Brown, has soured the word “militia” in the mouths of many Americans.

But the militia movement is growing. According to a
study published by the Southern Poverty Law Center in January, the number of active militia groups in the United States has risen by 37 percent since 2014.

To better understand why these groups exist, and what drives people to join them, IndyStar reporter Michael Anthony Adams was granted access to the Indiana Volunteer Militia, to give you an inside look at how its members train and prepare.

Call IndyStar reporter Michael Anthony Adams at (317) 444-6123. Follow him on Twitter:
@michaeladams317.


"Choose a job you love and you will not have to work a day in your life" (Confucius)

+2
Luis Miguel Goitizolo

1162
61587 Posts
61587
Invite Me as a Friend
Top 25 Poster
Person Of The Week
RE: ARE WE NOW IN THE END TIMES?
4/10/2016 11:57:10 PM
Chinese Researchers Experiment with Making HIV-Proof Embryos

The attempt is another controversial test of whether gene-modified people are possible

by Antonio Regalado April 8, 2016


Chinese fertility doctors have tried to make HIV-proof human embryos, but the experiments ended in a bust. The new report is the second time researchers in China revealed that they had a go at making genetically modified human embryos.


The controversial experiments are, in effect, feasibility studies of whether it’s possible to make super-people engineered to avoid genetic disorders or resist disease.

“It is foreseeable that a genetically modified human could be generated,” according to Yong Fan, a researcher at Guangzhou Medical University, who published the report.



His team collected more than 200 one-cell embryos and attempted to alter their DNA to install a gene that protects against HIV infection. The study, published two days ago in an obscure reproductive journal, was first spotted by reporters at Nature.

The scientists cautioned that they believe making actual genetically modified babies should be “strictly prohibited”—but perhaps only until the technology is perfected. “We believe that is necessary to keep developing and improving the technologies for precise genetic modification in humans,” Fan’s team said, since gene modification could “provide solutions for genetic diseases” and improve human health.

The Chinese scientists tried to make human embryos resistant to HIV by editing a gene called CCR5. It’s known that some people possess versions of this gene which makes them immune to the virus, which causes AIDS. The reason is they no longer make a protein that HIV needs to enter and hijack immune cells.

Doctors in Berlin demonstrated the effect after they gave a man sick from HIV a bone marrow transplant from a person with the protective gene mutation. The man—known since as the “Berlin patient”—was cured of HIV, too.

Using the gene-editing method called CRISPR, Fan and his team tried to change the DNA in the embryos over to the protective version of the CCR5 gene in order to show, in principle, that they could make HIV-proof people.

Almost exactly a year ago, in a world first, a separate group in Guangzhou
said that it had altered embryos in an effort to repair the genetic defect that causes a blood disease beta thalassemia.

That set off an ethical debate, and last December the U.S. National Academy of Sciences, along with British and some Chinese scientific leaders, said any attempt to make a gene-edited baby would be “
irresponsible,” a message that in many ways seemed directed at IVF doctors in China.

In February, U.S. officials went further, calling gene-editing a “
weapon of mass destruction” and making a point of singling out the earlier Chinese research.

One day endowing people with protective genes could become a real possibility. It would be like a vaccine, except one that is installed in a person’s genome from birth. And there’s a long list of genes people might demand for their children in addition to HIV resistance. One DNA change, for instance, seems to completely prevent Alzheimer’s. Another generates people with twice the muscle mass.

But that’s a ways off, and Fan’s team said its experiments essentially flopped. They only managed to successfully edit a handful of embryos, and even these ended up as “mosaics,” or a mix of cells, some of which had the new gene, and some that didn’t.

(Read more:
Nature, “Top U.S. Intelligence Official Calls Gene Editing a WMD Threat” “Scientists on Gene-Edited Babies: It’s 'Irresponsible' for Now,” “Chinese Team Reports Gene-Editing Human Embryos”)



"Choose a job you love and you will not have to work a day in your life" (Confucius)

+2