Combat in GTA 6 has evolved into something deeper, more tactical, and far more satisfying than its predecessors. With enhanced AI, improved gunplay mechanics, and more diverse enemy types, running into a fight without the right setup can mean a quick trip to the hospital—or worse, back to a checkpoint. To dominate the streets of Vice City and beyond, mastering your loadout is essential.

Here are 13 tried-and-tested loadouts designed to help you win firefights across different mission types, environments, and player-versus-player (PvP) encounters.

1. Urban Assault Loadout

• Assault Rifle

• Heavy Pistol

• Flashbang

• Kevlar Vest
  Perfect for tight city corners and alley shootouts. Good balance of mobility and firepower.

2. Stealth Operative

• Suppressed SMG

• Combat Knife

• Smoke Grenade

• Lightweight armor
  Ideal for quiet entries and sabotage missions. Helps avoid triggering alarms.

3. Close-Quarters Bruiser

• Shotgun (Pump or Auto)

• Sawed-Off Backup

• Tear Gas

• Combat Stimulant
  Especially effective indoors or during warehouse missions. High damage, fast takedowns.

4. Sniper Scout Setup

• Sniper Rifle

• Silenced Pistol

• Decoy Device

• Reinforced Scope Gear
  Control the battlefield from a distance. Combine this loadout with rooftop access.

5. Explosives Expert

• Grenade Launcher

• Combat MG

• Sticky Bombs

• Blast Protection Gear
  Useful during vehicle ambushes and enemy convoys. Also great for crowd control.

6. Speed Runner’s Kit

• Compact SMG

• Taser

• Adrenaline Boost

• Light Boots
  Great for time trials and missions where movement speed matters more than raw power.

7. Heavy Defense Loadout

• Minigun or LMG

• Heavy Revolver

• Armor Enhancer

• Reinforced Shield Module
  Used in holdout missions or when you're facing waves of NPCs.

8. Gangland Brawler

• Melee Weapon of Choice

• Revolver

• Molotovs

• Street Armor
  Low-profile and high style. Better for RP servers or street-level story arcs.

9. PvP Dominator Loadout

• Marksman Rifle

• Combat Shotgun

• Flashbang

• Reactive Armor
  This is the setup you want when you’re competing in free roam or public lobbies.

10. Night Ops Loadout

• Night Vision SMG

• Suppressed Pistol

• EMP Grenades

• Dark Gear Suit
  Missions involving nighttime infiltration or power grid sabotage demand this build.

11. Vehicle Combat Kit

• Compact Grenade Launcher

• Auto Shotgun

• Sticky Bombs

• Driving Gloves
  When you're gunning from a vehicle or in a convoy mission, this is the way to go.

12. Underwater Assault

• Harpoon Gun

• Diving Knife

• Waterproof Grenades

• Rebreather Unit
  Perfect for missions involving docks, shipyards, or underwater objectives.

13. Balanced Default Loadout

• Carbine Rifle

• Standard Pistol

• Flashbang

• Mid-Tier Armor
  If you're unsure what you’re walking into, this loadout will keep you prepared for most situations.

Fine-tuning your gear isn’t just about style—it directly affects your survival and efficiency. Whether you're taking down cartel operations, breaking into secure compounds, or battling it out with rival players, the right combination of weapons, equipment, and perks can turn you into a one-person army.

Many players also look to stretch their in-game funds smartly. If you're looking to gear up without grinding forever, some turn to options like buy gta 6 money or buy gta 6 money ps5 to save time—especially through trusted game services like U4N that understand the game’s economy and player needs.

Combat success in GTA 6 isn't just about reaction speed—it's about strategy. Set your loadouts, plan your missions, and step into Vice City like a pro.