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Jean Marie

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Information about a scary disease.... TNBC!
2/4/2009 6:31:04 PM

Breast Cancer....  the diagnosis will strike fear in over 240,000 women and 2,400 men this year...

Know what's even scarier?  When the diagnosis is TNBC - Triple Negative Breast Cancer.

Know why?

    To date, doctors know that most breast cancers are 
characterized by the presence of three receptors (proteins 
found inside or on the surface of breast cells): estrogen, 
progesterone and HER2. These receptors are not 
"expressed" in women with triple negative breast cancer - 
hence the name. Since most treatments available today 
are aimed at those receptors, TNBC is difficult to treat, 
and the tumors are often more aggressive. TNBC 
represents only 15 percent of all breast cancer cases 
but accounts for as many as 25 percent of all breast 
cancer deaths.
Many basal-like tumors are "triple negative cancers" which 
means they are estrogen receptor-negative (ER-), 
progesterone receptor-negative (PR-) and 
HER2/neu-negative (HER2-). 
This makes current treatment choices limited. 
Basal-like tumors are often aggressive and are associated 
with a poorer prognosis compared to the estrogen 
receptor-positive subtypes (luminal A, luminal B and 
normal breast-like tumors). 
Unfortunately, most often basal-like tumors are not eligible 
for treatment with Herceptin or hormonal therapies, like 
tamoxifen, because they are HER2/neu-negative and 
hormone receptor-negative. Because the genes associated 
with basal-like tumors are not well understood, targeted 
therapies do not yet exist. 
This is why I do what I do.... the research towards 
a cure must go on.... too many are fighting the battle for 
their lives.... too many have already lost their fight!
Please.... pass this information on.... share it with your 
friends.... If you are a woman.... STAY VIGILANT.... 
1 out of every 8 women will be diagnosed with breast 
cancer in her lifetime..... If you love a woman.... REMIND 
her  to get her annual check-up & mammogram. 
If you are a man,  you are NOT exempt.... 2,400+ men 
will be diagnosed with BREAST CANCER in the 
USA this year!
EARLY DETECTION is your BEST PROTECTION!
PLEASE, do whatever you can to raise awareness..... 
& if you are able, support our search for the cure!
Visit our websites for additional information, pictures, 
videos, and our PLACARD (the wall of honor & memory) 
at these websites:
http://www.3daydancers.com
http://www.the3day.org/goto/jmSD09
As always, thank you for your support & your love! It means
more than you know!
Hugs,
JeanMarie
 
JeanMarie http://www.3daydancers.com "May you live today from what you learned yesterday to achieve a better tomorrow"
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Nick Sym

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Re: Information about a scary disease.... TNBC!
2/4/2009 11:41:13 PM




Breast Cancer Awareness On My Site! http://www.freewebs.com/nicksym Free exposure that works http://www.webbizinsider.com/Home.asp?RID=55242
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Jean Marie

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Re: Information about a scary disease.... TNBC!
2/5/2009 3:48:38 AM

Thanks for the beautiful eagle, Nick!  So free, and rising above it all...  what a beautiful statement...

Hugs,

JeanMarie

JeanMarie http://www.3daydancers.com "May you live today from what you learned yesterday to achieve a better tomorrow"
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